Archive for September, 2008

Blood cord treatment shows incredible success

Friday, September 12th, 2008

A Colorado girl, diagnosed with Cerebral Palsy at age 1, has a new lease on life thanks to an experimental procedure.

According to a story in the Denver Post, Chloe Levine showed almost immediate improvement after receiving an infusion of her own stem cells. The frankly incredible success of the treatment furthers the foundations supporting the need for stem cell research and gives hope to thousands of children afflicted with Cerebral Palsy.

At birth, Chloe’s parents decided to "bank" the blood from her umbilical cord and it was that blood that worked this miracle. Prior to the treatment, Chloe suffered from an in utero stroke on the left side of her brain resulting in Cerebral Palsy. Within days after the treatment, she began to regain control of her body.

While this represents one of the most optimistic outcomes, researchers insist that only a baby’s own umbilical cord stem cells cold have worked this well.

The dangers of Botox

Friday, September 12th, 2008

It turns out that the popular cosmetic treatment Botox may have some ugly side effects, especially when used for off-label treatments. A class action lawsuit has been filed in California by Botox users against its manufacturer, Allergan Inc., alleging failure to warn, along with several other individual cases.

The lawyers for the plaintiffs in California claim three deaths associated with Botox use. In Texas, a 69-year-old nurse died after getting Botox injections for her neck and shoulder pain, as well as a 7-year-old girl with cerebral palsy who was receiving the shots to control the spasms caused by her disease. In Arizona, a 71-year-old woman died after losing the ability to speak or swallow, most likely caused by a cosmetic Botox treatment she received in a mall clinic.

Botox comes from botulinum toxin Type A, which in its raw form, is a very deadly poison. It was approved by the Food and Drug Administration almost 20 years ago for soothing wrinkles. The FDA warned back in back in February that they were investigating reports of serious reactions in botulinum-based drugs such as Botox and Myobloc.

The consumer group Public Citizen reports 16 deaths due to Botox (or Myobloc) between 1997 and 2006 as well as 180 patients that developed life-threatening conditions and 87 hospitalizations.

Most reports of adverse side-effects due to Botox treatment have come out of off-label use. Though Botox is essentially only approved to treat wrinkles, some doctors use it to treat migraines, spasms and pain.

Study: Fertility treatments could cause gene mutations

Wednesday, September 3rd, 2008

According to a recent Chinese study, the use of in vitro fertilization (IVF) or another assisted fertility technique called intracytoplasmic sperm injection (ICSI) to conceive appears to increase the odds of Y-chromosome birth defects, or "microdeletions," in male offspring.

The report, which was published by Reuters notes this particular process is used primarily to overcome male infertility.

According to Reuters, such deletions could result in birth defects like defective sperm production and possibly also hypospadias — a common birth defect of the penis that occurs when the urinary outlet develops on the underside of the penis rather than at the tip.

Previous research has linked IVF to low birth weight, preterm delivery, cerebral palsy, and major birth defects, leading some researchers to theorize these therapies may cause gene mutations.

The study was small and the results are preliminary, and larger studies must still be conducted. However, the study highlights the genetic dangers  of assisted reproductive technology.