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Archive for the ‘Premature Birth’ Category

Final weeks of pregnancy are critical

Tuesday, February 3rd, 2009

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Babies born just a few weeks prematurely are more than three times as likely to have cerebral palsy than full-term infants. In fact, those last few weeks of pregnancy are critical to a child’s health and development.

New research indicates that late preterm infants (those born 34-36 weeks gestation) had a much higher risk of developmental delays than babies born full-term.

The earlier an infant is born, the higher the risk of some neuro-developmental problems, the research shows. For example, infants born between 30 and 33 weeks gestation were nearly eight times as likely as full-term infants to have cerebral palsy. This adds to the growing body of evidence showing that being born just a few weeks too soon can have lasting consequences that can no longer be described as temporary or benign. These findings reinforce the message that a few extra weeks of pregnancy can have a beneficial effect to an infant’s health.

Late preterm babies account for more than 70 percent of all preterm births and for the majority of the increase in preterm birth rates during the past two decades. Late preterm infants have a greater risk of birth defects, breathing problems, feeding difficulties, temperature instability (hypothermia), jaundice, delayed brain development and death than babies born at term. This new analysis shows that these late preterm infants also have three times the risk of cerebral palsy and a slightly higher risk of mental retardation.

Exactly what causes the increased risk of birth defects like cerebral palsy and neuro-developmental delays in late preterm infants should be the subject of future research. However, there are several theories, including risk factors during the pregnancy that may contribute to damage in utero, or complications related to the preterm birth.

Epsom salts can reduce cerebral palsy risk

Tuesday, February 3rd, 2009

Magnesium sulfate (epsom salts) can reduce a premature infant’s risk of developing cerebral palsy by 50 percent.

The result of the new study,  recently completed at University of Alabama-Birmingham and the University of North Carolina-Chapel Hill, promises to be the biggest breakthrough in the management of high-risk pregnancies in 30 years.

Magnesium sulfate is a chemical compound with a wide variety of medical uses. While it cannot prevent the onset of premature birth, it is well known to help regulate maternal blood pressure.

Cerebral palsy is a blanket term for birth defects that can lead to a variety of movement and posture disorders caused by damage to the developing brain. Approximately one-third of all cases are linked to brain damage caused during premature birth – defined as occurring before the 32nd week of pregnancy.

The researchers emphasized that study’s findings only apply to premature births, but said that the observed effect was large enough to warrant immediate implementation. In addition, he study’s results were consistent with those of the second largest study ever conducted, a 2003 trial from Australia.
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Scientists remain uncertain exactly how magnesium sulfate acts to reduce cerebral palsy risk. They have speculated that it might protect a fetus from injury or damage caused by inflammation, swelling, or lack of oxygen, or that it might "stabilize the vessels in the vulnerable preterm brain."

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California hospital specializes in treating the infant brain

Wednesday, November 19th, 2008

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The University of California Children’s Hospital in San Francisco has opened a new department that focuses on the infant brain.
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It is the first facility of its kind in the United States. The department brings together specialized treatment for infants who show signs of brain damage at birth – and are at-risk for developing cerebral palsy, mental retardation and other cognitive disorders – with clinical research.

The new Neuro-Intensive Care Nursery (NICN) is a state-of-the-art newborn care unit designed to host clinical trials and bring the latest cutting-edge treatments to patients.
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Newborn brain damage is the leading cause of mental retardation, developmental delay and cerebral palsy in the U.S., according to Rowitch. Among all babies born very prematurely, five to 15 percent go on to develop cerebral palsy, and 25 to 50 percent develop cognitive disorders or a learning disability. The cost of treating cerebral palsy alone exceeds $35 billion annually, according to the March of Dimes Foundation.

The opening of the NICN comes at an important time, as the last few decades have seen an increase in the number of infants who show signs of brain damage shortly after birth. This increase is primarily due to a corresponding increase in the survival rate of extremely premature infants – known to be much more susceptible to brain damage than full-term infants.

Although advanced neonatal care has enabled doctors to keep preterm infants alive, there is currently a lack of therapies that prevent or diminish brain damage in these cases. There is hope that the work done at the NICN will play an instrumental role in the development of new therapies for premature babies at high risk for brain damage.

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