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Posts Tagged ‘birth defect’

Anticonvulsant Medication Depakote Associated With Serious Birth Defects

Thursday, April 28th, 2011

According to the San Francisco Gate, anticonvulsant medication such as Depakote are being increasingly linked to birth defects. Recent studies have found that victims of birth defects may have been exposed to anticonvulsants in the uterus. Mothers may have been prescribed Depakote which has the risk of potentially causing life-long conditions such as spina bifida, heart malformations or oral cleft birth defects.

Depakote is a widely used anticonvulsant drug on the market, prescribed to women suffering from epilepsy and migraine headaches. A report entitled The Teratogenicity of Anticonvulsant Drugs done by the New England Journal of Medicine suggests a connection between Depakote use and the development of birth defects among infants exposed to the drug during pregnancy. The Food and Drug Administration supports these findings and published its own report Birth Defects Related to Depakote and Similar Drugs.

The report is a compilation of studies conducted on adverse effects of Depakote use during pregnancy. Among the birth defects found to be closely associated with the drug are severe and potentially fatal injuries and neural tube birth defects such as spina bifida. These birth defects have no cure and require life-long costly medical treatment. Sometimes extensive medical treatment is necessary to alleviate an infant’s symptoms associated with the condition.

In 2009, the FDA issued a warning about Depakote directed towards healthcare professionals and prescribing of the drug to women during pregnancy. The agency warned medical professionals and women of the increased risk of birth defects among infants exposed to the drug in the uterus including malformed face and skull, spina bifida, spinal cord defects, and cardiovascular malformations.

Study Finds Decline in Infant Cerebral Palsy

Tuesday, April 26th, 2011

According to Seedol, a study conducted by a team of researchers in the Netherlands suggests a decline in the number of children diagnosed with cerebral palsy. The study findings were published in the journal of Pediatrics concluded that promising developments have been made in recent years in terms of cerebral palsy diagnosis and their severity on infants born prematurely.

The study conducted by the University Medical Center Utrecht examined 3,000 children born prematurely, a group commonly susceptible to being diagnosed with cerebral palsy, over a 15-year period from 1990 to 2005. The researchers found that 6.5 percent of the infants born between 1990 and 1993 were diagnosed with the birth injury, while only 2.2 percent of infants born between 2002 and 2005 received a similar diagnosis.

The decline could be attributed to technological and medical advances, study authors suggest. Advances in perinatal and neonatal care may have contributed to the decline, while the improvement in those fields has also lessened the severity of the condition in many of the patients.

Cerebral palsy is a common birth injury that can harshly damage the brain of an infant. Some birth injuries can happen naturally, where others can happen due to medical negligence during birth. Birth injuries inflicted during the birthing process may come from respiratory failure, c-section error, lack of oxygen, fetal distress and other birth trauma.

Hospital Watchdog Warns of Early Cesarean Deliveries and Birth Injuries

Monday, February 28th, 2011

The Leapfrog Group, a voluntary patient-safety program, said that early elective deliveries might put infants at an increased risk of birth injuries. The group presented its finding to inform parents-to-be about the risks of elective early deliveries.

The group states some hospitals across the country are delivering 40 percent of newborn babies early for no medical reason. Among the 773 hospitals in the United States, the group found a wide range of inconsistencies between how often facilities performed early elective deliveries. Additionally, allowing early deliveries may result in higher birth injury, infant mortality rates and permanent health problems, the group claims.

An early elective delivery is a cesarean section, a surgical procedure made through a pregnant mother’s abdomen to deliver a baby. Medical experts recommend a cesarean section when a vaginal delivery may pose a health risk to mother or baby, or in cases of multiple births. The Leapfrog Group found that some medical facilities had more than 40 percent of early elective deliveries for no medical reason, meaning a vaginal delivery would have been safe for mother and baby.

Leapfrog is urging hospitals nationwide to reduce their early elective delivery rates to less than 12 percent. Additionally, the group urges that infants must not be born before 29 weeks unless medically necessary, which is what most medical experts practice.

Brain Hibernation for Stroke Victims

Thursday, February 17th, 2011

According to Nursing Times, researchers have made recent claims that lowering the temperature of the brain could help victims of stroke by preventing death or disability from occurring.

A group of these researchers are seeking to acquire funding for a trial in 21 countries in Europe, involving 80 hospitals. They hope to reach 1,500 patients.

Lowering the temperature of the brain puts it into a state of hibernation, causing it to require less oxygen. This reduces damage and gives doctors more time to deal with damaged blood vessels.

Currently, doctors use this same technique of putting the brain into hibernation for patients who have an elevated risk of brain damage, either due to cardiac health issues or due to birth defects.

Dr. Malcom Macleod of the Centre for Clinical Brain Sciences at the University of Edinburgh notes that one European dies from a stroke every 90 seconds. Approximately double that amount of people will survive a stroke every day, but will be disabled.

Dr. Macleod also adds that medically induced “hypothermia might improve the outcome for more than 40,000 Europeans every year.”

Though the trial could be expensive, Dr. Stefan Schwab of the Friedrich-Alexander-University in Germany notes that the benefits of the trial would allow it to pay for itself within a year.

Dr. Schwab hopes that this trial will open the door for many additional trials and treatment options involving beneficial medically induced hypothermia, resulting in even more lives saved as the European population ages.